Pearls & Oy-sters: Tacrolimus neurotoxicity presenting as an isolated brainstem lesion.

Pearls and oy-sters: reversible Ondine's curse in a case of lateral medullary infarction.

Ondine's curse is an eponym that refers to central alveolar apnea/hypopnea observed among patients with acquired or congenital brainstem disorders. This condition results in loss of automatic and/or voluntary respiration with characteristic polysomnographic finding of impaired ventilator responses to hypercapnia and sleep apnea, which are more pronounced during non-REM sleep, less in REM sleep,...

Pearls & Oy-sters: polycythemia vera presenting with ischemic strokes in multiple arterial territories.

Pearls & oy-sters: cerebral venous air embolism after central catheter removal: too much air can kill.

Pearls & Oy-sters: cough headache secondary to Chiari malformation type I.

Pearls & Oy-sters: Symptomatic innominate artery disease.

1. Innominate artery (IA) disease is an uncommon cause of stroke. A comprehensive clinical evaluation can promptly provide important diagnostic information and help tailor a straightforward diagnostic strategy. 2. The tetrad of right arm, eye, and hemispheric and posterior circulation ischemia is highly suggestive of an IA lesion. 3. Revascularization may be safely performed using an endovascul...